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Vasculitis

INFORMATION ON VASCULITIS:-
Vasculitis may be defined as inflammation of blood vessels, which as a result includes its image in veins, arteries and capillaries. Vasculitis is also called angiitis. Vasculitis can change architecture of walls of blood vessels, such as thickening, weakening, narrowing and scarring. Inflammation can be short-term (acute) or long-term (chronic) and can be so severe that the tissues and organs supplied by the affected vessels don't get enough blood. The shortage of blood can result in organ and tissue damage, even death.

CAUSES OF VASCULITIS:-
The consequences which are responsible for the development of Vasculitis are:-
1. Inflammation.
2. Hepatitis C virus.
3. Hepatitis D virus.
4. Side effect of certain medicines.
5. Disease of immune system.

SYMPTOMS OF VASCULITIS:-
1. Fever.
2. Fatigue.
3. Weight loss.
4. Muscles and joint pain.
5. Loss of appetite.

DIAGNOSIS OF VASCULITIS:-
Clinically Vasculitis can be identified by:-
1. Blood test.
2. MRI.
3. CT scan.
4. X- Ray.
5. Biopsy of blood vessels.
6. Urine test.

TREATMENT OF VASCULITIS:-
Treatment for many types of Vasculitis includes doses of a corticosteroid drug such as prednisone or methylprednisolone. Subject start feeling better in just a few days, but he/she may need to continue taking medication for an additional period of time. After the first month, doctor may gradually begin to lower the dose until subject reaches the lowest dose of corticosteroids. Some of your signs and symptoms may return during this tapering period.

Some cases of Vasculitis are severe or we can say that don't respond well to corticosteroids. Then Vasculitis disease must be treated with cytotoxic drugs, such as azathioprine and cyclophosphamide. Cytotoxic drugs suppress the inflammation in blood vessels. Mycophenolate mofetil is another immunosuppressant used to prevent transplant rejection.

 

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