INFORMATION ON SJOGREN'S SYNDROME

Sjogren’s syndrome is a chronic disease in which white blood cells attack the moisture-producing glands. The hallmark symptoms are dry eyes and dry mouth, but it is a systemic disease, affecting many organs and may cause fatigue. It is one of the most prevalent autoimmune disorders, striking as many as four million Americans. Sjogren's syndrome that involves the gland inflammation, but not associated with a connective tissue disease, is referred to as primary Sjogren's syndrome. Secondary Sjogren's syndrome involves not only gland inflammation, but is associated with a connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma.

SYNONYMS OF SJOGREN'S SYNDROME

Synonyms and related keywords:-
 
Sjogren's syndrome
Sicca complex
Gougerot-Sjögren disease
Sicca syndrome
Xerostomia
Lymphocytic infiltration of the exocrine glands

CAUSES OF SJOGREN’S SYNDROME

The cause of Sjogren’s syndrome is unknown. Sjogren's syndrome can occur alone or can be associated with other conditions such as rheumatoid arthritis, systemic lupus erythematosus and other so called connective tissue diseases.

SYMPTOMS OF SJOGREN’S SYNDROME

Symptoms may include:

Dry or itching eyes
Dryness of the mouth
Difficulty swallowing
Loss of sense of taste
Severe dental cavities
Hoarseness
Fatigue
Joint pain or joint swelling
Swollen glands
Cloudy cornea

DIAGNOSIS OF SJOGREN'S SYNDROME

Medical exam
Lab tests
Chest X-rays
Lip biopsy
Schirmer test/slit-lamp exam
Urine test

TREATMENT OF SJOGREN'S SYNDROME

There is no known cure for Sjogren's syndrome nor is there a specific treatment to restore gland secretion. Nonsteroidal anti-inflammatory drugs may be used to treat musculoskeletal symptoms. For individuals with severe complications, corticosteroids or immunosuppressive drugs may be prescribed.

Other treatment may be used:-

Medications: aspirin, plaquenil
Exercise
For dry mouth, sip water throughout the day; seek treatment for oral yeast infections; use saliva substitutes
For dry eyes, use artificial tears, eye ointments.
For dry skin, use moisturizers
For vaginal dryness, use lubricating jelly