INFORMATION ON LEIGH’S DISEASE:-

Leigh’s disease may be defined as a rare inherited neurometabolic disorder characterized by degradation of the central nervous system.

CAUSE OF LEIGH’S DISEASE:-

The main cause of Leigh’s disease is defects of genetically determined enzyme

SYMPTOMS OF LEIGH’S DISEASE:-

1. Poor sucking ability.
2. Loss of head control.
3. Loss of appetite.
4. Vomiting.
5. Irritability, continuous crying, and/or seizures.
6. Generalized weakness.
7. Lack of muscle tone.
8. Impairment of respiratory and kidney function.

DIAGNOSIS OF LEIGH’S DISEASE:-

Clinically Leigh’s disease can be detected by:-

1. Biopsy.
2. Genetic testing.
3. Blood test.
4. CT scan.

TREATMENT OF LEIGH’S DISEASE:-

Currently, there is no treatment that is effective in slowing the progression of Leigh’s disease. Medicines containing Thiamine or vitamin B1 are usually preferred. Sodium bicarbonate may also be prescribed to help manage lactic acidosis.