INFORMATION ON KEARNS-SAYRE SYNDROME:-

Kearns-Sayre syndrome is a rare neuromuscular disorder which results in abnormalities in the DNA of mitochondria - small rod-like structures found in every cell of the body that produce the energy that drives cellular functions.

SYNONYMS OF KEARNS-SAYRE SYNDROME:-

1. Oculocraniosomatic neuromuscular disease.
2. Ragged red fiber disease.
3. Ophthalmoplegia-plus.
4. Hereditary external ophthalmoplegia.

CAUSES OF KEARNS-SAYRE SYNDROME:-<

Kearns Sayre syndrome is caused by problems with the genetic material in body cells. Specifically, Kearns Sayre syndrome is due to defects in the DNA in mitochondria. Kearns Sayre syndrome is not inherited.

SYMPTOMS OF KEARNS-SAYRE SYNDROME:-

1. Muscle weakness.
2. Difficulty walking or moving.
3. Brain damage.
4. Deafness.
5. Heart disease.
6. Short stature.
7. Small sex organs.
8. Paralysis of certain eye muscles.
9. Degeneration of the retina.

DIAGNOSIS OF KEARNS-SAYRE SYNDROME:-

Clinically Kearns-Sayre syndrome can be diagnosed by:-

1. Blood test for protein and lactose level.
2. Biopsy.

TREATMENT OF KEARNS-SAYRE SYNDROME:-

Treatment for Kearns-Sayre syndrome is mainly symptomatic and supportive. Cardiac abnormalities may be treated with various cardiac drugs or a pacemaker.