INFORMATION ON INCLUSION BODY MYOSITIS

Inclusion body myositis is a muscle disease described by progressive muscle weakness and wastig.
Falling and tripping are the first noticeable symptoms of Inclusion body myositis. For some of the patients the disorder begins with weakness in the hands causing difficulty with gripping, pinching, and buttoning
Inclusin body myositis occurs more frequently in male then in female and it affects both the proximal and distal muscles as it mostly begin after age of 50. Under this there may be weakness in wrist and finger muscles and atrophy of the quadricep muscles in the legs.

CAUSES OF INCLUSION BODY MYOSITIS

Inclusion Body Myositis is cause by:

1. Inflammation of the muscles
2. Inherited conditions, especially muscular dystrophies
3. Problems with certain hormones that affect muscle function
4. Chemical imbalances in the body
5. Drugs and toxic substances
6. Infections

SYMPTOMS OF INCLUSION BODY MYOSITIS

1. Progressive muscle weakness
2. Muscle atrophy
3. Falling
4. Tripping
5. Hand weakness
6. Difficulty gripping
7. Difficulty pinching
8. Difficulty buttoning
9. Proximal muscle weakness
10. Distal muscle weakness
11. Wrist weakness
12. Finger muscle weakness
13. Quadricep muscle atrophy
14. Forearm atrophy
15. Difficulty swallowing

DIAGNOSIS OF INCLUSION BODY MYOSITIS

Clinically inclusion body myositis can be diagnosed by:-

1. muscle biopsy
2. Blood tests
3. Electromyography
4. Muscle biopsy
;

TREATMENT OF INCLUSION BODY MYOSITIS

At present no treatment is available against the different forms of Inclusion body myositis. Some use the drug therapy with combination of corticosteroids and methotrexate or human intravenous immunoglobulin.
New therapeutic protocols are currently being tested. Physical therapy, occupational therapy, and ergo therapy are commonly prescribed.
There have been several attempts to use different medications to treat Inclusion body myositis but in clinical trials, although some have produced minor short term improvements, none has been shown to be effective in the long term.
New treatments named Biologic agents are being developed to treat immune disorders.