INFORMATION ON HEREDITARY NEUROPATHIES

Hereditary neuropathies are a group of inherited disorders of the peripheral nervous system. It may be defined as a neurological disorder which is characterized by progressive weakness with multifocal distribution. We can also say that Hereditary Neuropathies is a progressive muscle disorder characterized by muscle weakness in the hands, with differences from one side of the body to the other in the specific muscles involved.

SYNONYMS OF HEREDITARY NEUROPATHIES

Synonyms and related keywords:

1. Neuropathy - Hereditary.
2. Hereditary Sensory and Autonomic.
3. Hereditary Sensory Radicular.
4. Autosomal Dominant.

CAUSES OF HEREDITARY NEUROPATHIES

These disorders mainly caused by degeneration of the insulation that normally surrounds the nerves and helps them conduct the electrical impulses needed for them to trigger muscle movement. Patient’s genetic condition, that is passed down through the family is also a cause of this disorder.

SYMPTOMS OF HEREDITARY NEUROPATHIES

Symptoms of Hereditary neuropathies:

1. Scoliosis.
2. Muscle weakness.
3. Thin lower legs.
4. Foot deformities.
5. Insensitivity to pain.
6. Skin blotching and impaired sweating.
7. Numbness and tingling in the feet and hands.

DIAGNOSIS OF HEREDITARY NEUROPATHIES

Diagnosis of Hereditary neuropathies may include nerve biopsies, Nerve conduction studies, and genetic testing. These disorders may be diagnosed as early as birth or as late as middle or late age. The other clinical diagnostic approach is elements that point to a neuropathy of inherited origin, different modalities of presentation, laboratory and instrumental diagnostic tests.

TREATMENT OF HEREDITARY NEUROPATHIES

As yet, there is no standard treatment for this disorder. However, treatment of hereditary neuropathies is symptomatic and supportive and may include orthopedic surgery and bracing to improve mobility, and measures to protect against stress fractures-particularly in the feet and legs. And genetic counseling is available now.