INFORMATION ON GENETIC BRAIN DISORDERS
More than a thousand genetic disorders that lead to abnormalities of brain structure and function have now been identified. They include a large number of neurometabolic disorders such as Adrenoleukodystrophy, Barth Syndrome, birth defects, brain malformations, epilepsy, Fragile-X, HPE, mitochondrial disorders, Rett Syndrome, and Smith-Lemli-Opitz Syndrome, in which the precise biochemical disturbance has been identified.
People with this mutation are at great risk for developing blood vessel lesions in the brain and their associated symptoms, as are their future children. The finding paves the way for a new genetic test for the rare, familial disease, which typically lies dormant in patients for decades before its potentially devastating symptoms appear, said the researchers. The vessel lesions in the brain can cause seizures, severe headaches, hemorrhagic stroke and neurological deficits. Affected individuals have a 50 percent chance of passing the disease on to their children.
SYNONYMS OF GENETIC BRAIN DISORDERS
1 Hallervorden-Spatz Syndrome
2 Pantothenate Kinase Associated Neurodegeneration
3 Pigmentary Degeneration of Globus Pallidus
4 Substantia Nigra
5 Arrhinencephaly
6 Familial alobar holoprosencephaly
CAUSES OF GENETIC BRAIN DISORDERS
Doctors believed that depression was the result of thoughts or emotions that were troubling for a person. But now experts realize that there can be several factors working together that will lead a person to become depressed. The three most important of these are biological, genetic, and environmental factors.
Biological causes are due to changes in the chemistry of the brain, such as fluctuations in the levels of important hormones. Genetic causes are the result of what you inherit from your parents.
SYMPTOMS OF GENETIC BRAIN DISORDERS
People with this mutation are at great risk for developing blood vessel lesions in the brain and their associated symptoms, as are their future children
Behavioral and emotional are
1. Irritability
2. Depression
3. Anxiety
4. Aggressive outbursts
5. Mood swings
6. Social withdrawal
Some others:
1. Depression
2. Forgetfulness
3. Impaired judgment
DIAGNOSIS OF GENETIC BRAIN DISORDERS
At this time, there is no way to stop or reverse the course of brain disorder. There is no
Treatment to halt the progression, which leads to death after ten to twenty-five years.
However, now that the brain disorder gene has been located, investigators are continuing
to study the brain disorder gene with an eye toward understanding how it causes disease
in the human body.
Research confirms that determining the genetic composition of brain cancers can better inform doctors and patients about treatment options and prognosis. The findings could change the future of how cancers are diagnosed.
TREATMENT OF GENETIC BRAIN DISORDERS
Potential treatments are described for informational purposes only. You should consult with your physician for medical advice about individual cases.
