INFORMATION ON CAROLI DISEASE:

Caroli disease is rare in occurrence. It is a disease in which a subject’s saccular, dilated segments of the intrahepatic bile ducts lead to stone formation in company with recurrent cholangitis and hepatic abscesses with sepsis. Caroli disease is very common in childhood and young adult life.


SYNOMS OF CAROLI DISEASE:-
1. Congenital Dilatation of Intrahepatic Bile Duct


CAUSES OF CAROLI DISEASE:-

The specific cause of Caroli disease has not been discovered however, a genetic cause is likely in Caroli Disease.
This genetic cause may be mutation in genes or autosomal recessive pattern.


SYMPTOMS OF CAROLI DISEASE:-

1. Jaundice.
2. Fever.
3. Abdominal pain.
4. Nausea & vomiting.

DIAGNOSIS OF CAROLI DISEASE:-

1. Ultrasonography.
2. Nuclear scintigraphy.
3. CT scan.
4. MRI.
5. Liver functioning test.
6. Biopsy.


PREVENTION OF CAROLI DISEASE:-

Prevention of Caroli disease can be prevented by two methods:

1. Medicinal treatment.
2. Operational treatment.


Medicinal treatment of Caroli Disease:-

Medicinal treatment of Caroli disease can be done with the help of antibiotics when the subject is in very early stage of Caroli disease.

Antibiotics with broad spectrum agent are very important.


Operational treatment of Caroli Disease:-

Operational procedure of Caroli disease includes the drainage procedure with endoscopic retrograde cholangiopancreatography (ERCP) or percutaneous transhepatic cholangiography (PTC).

Sphincterotomy can aid biliary drainage and stone removal. Liver transplantation can also come into play. This is the best alternative when recurrent cholangitis is not present.